There are many natural compounds with potential and demonstrated benefits to inflammatory factors of injury and illness. Today, it is not sufficient to merely show an end benefit on health outcomes, but it also is important to detail, as much as possible, the underlying mechanisms relative to inflammation. Download INSIDERs Cooling the Fires Digital Issue to explore the latest research on natural compounds with anti-inflammatory benefits, and for a close look at the market for anti-inflammatory ingredients. Takeaways include: *The inflammatory response is a part of the immune system and is mediated by several compounds, called eicosanoids. *Chronic inflammation has been determined an underlying factor in chronic illness. *Researchers have focused on how inflammation starts, progresses and ends, and how ingredients affect these mechanisms.