A proprietary form of alpha-ketoglutarate led to significant health improvements in mice. What is the potential for human longevity?

Todd Runestad, Content Director, NaturalProductsInsider.com

September 9, 2020

1 Min Read
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The fountain of youth has been sought for centuries. In the last two decades some ingredients—namely resveratrol and NAD+—have gained notoriety for an ability to lengthen the time study organisms live. The question is always whether the natural bioactives work in humans. It’s all but impossible to conduct a 40- or 50-year human clinical trial, so what now? In this Healthy Insider Podcast, senior editor Todd Runestad sits down with veteran anti-aging researcher Brian Kennedy, director of the Center for Healthy Longevity at the National University of Singapore, to discuss:

  • The difference between lifespan and healthspan—and how the latter may be more important.

  • Biomarkers that can be regulated and which contribute to what is known as the biological clock.

  • What alpha-ketoglutarate (LifeAKG) did in study results in a landmark study published Sept. 1in Cell Metabolism.

About the Author(s)

Todd Runestad

Content Director, NaturalProductsInsider.com, Natural Products Insider

Todd Runestad has been writing on nutrition science news since 1997. He is content director for NaturalProductsInsider.com and Natural Products Insider digital magazines. Other incarnations: supplements editor for NewHope.com, Delicious Living!, and Natural Foods Merchandiser. Former editor-in-chief of Functional Ingredients magazine and still covers raw material innovations and ingredient science.

Connect with me here on LinkedIn.


Todd writes about nutrition science news such as this story on mitochondrial nutrients, innovative ingredients such as this story about 12 trendy new ingredient launches from SupplySide West 2023, and is a judge for the NEXTY awards honoring innovation, integrity and inspiration in natural products including his specialty — dietary supplements. He extensively covered the rise and rise and rise and fall of cannabis hemp CBD. He helps produce in-person events at SupplySide West and SupplySide East trade shows and conferences, including the wildly popular Ingredient Idol game show, as well as Natural Products Expo West and Natural Products Expo East and the NBJ Summit. He was a board member for the Hemp Industries Association.

Education / Past Lives

In previous lives Todd was on the other side of nature from natural products — natural history — as managing editor at the Denver Museum of Nature & Science. He's sojourned to Burning Man and Mount Everest. He graduated many moons ago from the State University of New York College at Oneonta.


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