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From conflicting media reports to their own failed attempts to shed or keep off excess pounds, many consumers have become skeptical about the efficacy and safety of supplements to support weight loss. Globally, consumer attitudes toward dieting and weight management are shifting to more holistic, health-focused ideals, and the use of efficacious products with research-backed ingredients. Caffeine, probiotics, soy, Garcinia cambogia, and extracts from green tea or hot peppers are at the forefront of many formulations. Takeaways include: *Worldwide, levels of obesity have more than doubled since 1980. *Snack, bite and diet are the most popular terms among recent category trademark applications. *Individual genome testing linked to body weight and fitness is opening doors to personalized nutrition.