Natural Products Insider is part of the Informa Markets Division of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC's registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

Hawthorn Fights Cataract

<p> </p>

TIANJIN, China-- Hawthorn extract has antioxidant effects that may help fight cataract development, according to a new study (Biol Trace Elem Res. ePub 2010 Jul 2. DOI: 10.1007/s12011-010-8752-8). A research team from the Tianjin University of Traditional Chinese Medicine looked to evaluate the anticataract potential of Crataegus pinnatifida (hawthorn tree) leaf extract in vivo and its antioxidant effects in vitro. The in vitro antioxidant assay found the extract strongly inhibited aldose reductase and nitric oxide (NO) production, while showing oxygen radical scavenging activities; the team attributed the activity to nine major flavonoids found in the leaf extract.

Based on the in vitro results, the researchers prepared C. pinnatifida leaf extract eye drops in an 0.1 percent hydroxypropyl methyl cellulose solution. The eye drops were administered three times per day in rat pups undergoing selenite-induced oxidative ocular stress. Hawthorn extract increased serum superoxide dismutase (SOD) and catalase (CAT) antioxidant enzyme activity, and reduced malondialdehyde (MDA) oxidation levels compared with control animals. Further, activity of SOD, CAT and glutathione in the lens was significantly increased.

Hide comments


  • Allowed HTML tags: <em> <strong> <blockquote> <br> <p>

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.