A new study showed that Wellmune WPG, and immune health ingreident for foods, beverages and supplements from Biothera, uses distinct receptors and signaling pathways in certain white blood cells to induce cytotoxic function (Glycobiology. 2014 Jan 16. [Epub ahead of print]). Wellmune WGP is a yeast-derived beta glucan that boosts innate immune cells to keep the body healthy. The new research discusses how structurally different forms of yeast beta glucans use different receptors and associated signaling pathways to activate innate immune functions.
In the study, different forms of Biothera beta glucan were used to activate human peripheral blood mononuclear cells and oxidative burst, one of the cytotoxic mechanisms used by innate immune cells. Both particulate and soluble forms of Biothera beta glucans  bound to either complement receptor 3 (CR-3) or receptor Dectin-1 to initiate an immune response. These physically different forms of beta glucan induced this functional response through both overlapping and distinct signaling pathways.
Wellmune WGP is a proprietary bakers yeast beta 1,3/1,6 glucan that is clinically proven to prime key immune cells. It has global regulatory approval, including GRAS (generally recognized as safe) status in the U.S. and novel foods approval in Europe and China. It is patented, Kosher, Halal, non-allergenic and GMO-free.