Zinc Deficiency Seen in ADHD

OSIJEK, CroatiaZinc deficiency likely impacts the development of attention deficit hyperactivity disorder (ADHD) in children, according to a review out of Osijek University Hospital (Acta Med Croatica. 2009 Oct;63(4):307-13). The research team noted zinc serves as an essential cofactor of more than 100 enzymes that are necessary for basal metabolism, impacts the production and function of neurotransmitters and prostaglandins, and is important to maintaining the structure and function of the brain. Preliminary investigations have shown many children with ADHD have lower concentrations of zinc compared to healthy children, although zinc deficiency may not play a causative role. However, zinc supplementation on its own or combined with ADHD therapy could support brain function, possibly by supporting the production and utilization of dopamine to address hyperactivity. Because zinc also serves as a coenzyme of delta-6 desaturase, an enzyme the supports the anabolism of polyunsaturated long-chain fatty acids, zinc deficiency could impair the production of key fatty acids that support the health of the neuronal membranes.