New Mannitol Production Technique Developed by ARSNew Mannitol Production Technique Developed by ARS
May 23, 2005
New Mannitol Production Technique Developed by ARS
A newproduction method for mannitol, based on bacterial fermentation, has beendeveloped by the Agricultural Research Service (ARS), the chief scientificresearch agency of the U.S. Department of Agriculture (USDA), in conjunctionwith Chicago-based zuChem Inc.
The new production method involves feeding high-fructose corn syrup to Lactobacillusintermedius bacteria in a deep-tank fermentor; withinseveral hours, the bacteria convert 72 percent of the syrup into mannitol. ARSobtained a patent (U.S. 6,855,526, B2) on the process in February.
In 2004, zuChem successfully petitioned the Food and Drug Administration(FDA) to approve mannitol produced by microbial fermentation.
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