Creatine Studies at Experimental Biology 2003
SAN DIEGO--At the 2003 Experimental Biology meeting held here April 11 to 15, several studies in the area of performance nutrition and creatine were presented.
In the first study, which was presented by researchers from Numico Research in Wageningen, The Netherlands, 35 male subjects completed two 30-second sprints separated by four minutes of rest. Afterward, they were given one of three regimens four times daily: 5 g of creatine, 2.6 g of citrate and 2.7 g of sodium phosphate (as Boca Raton, Fla.-based Met-Rx's Creaphos); 5 g of creatine; or a placebo.
Prior to supplementation, peak power and total work were not different between groups; and, during the first sprint, supplementation had no effect on performance. During the second sprint, however, peak power increased in the Creaphos group compared to the placebo group, and total work increased in both creatine groups. Gain in body mass was greater in the Creaphos group over the creatine-only group.
In the second study, researchers from Belgium and England reported creatine did not appear to stimulate muscle protein synthesis independently. In a study of six men, quadriceps biopsies were taken after exercise at baseline and two weeks later after five days of taking 20 g/d of creatine. Although strenuous exercise stimulated muscle protein synthesis, the effects were not seen to increase after creatine supplementation.
Another study conducted at Victoria University, Australia, indicated the combination of whey and creatine increased strength, lean mass and muscle mass. Researchers examined the effects of 11 weeks of resistance training on 31 subjects in one of four supplement groups (taken in amounts of 1.5 g/kg/d): creatine and carbs, whey only, creatine and whey, or carbs only. While all groups increased strength, lean mass and muscle, the creatine plus whey group demonstrated a greater increase. This study was sponsored by Golden, Colo.-based AST Sports Science.
These studies and others can be found at www.faseb.org.