January 12, 2011

2 Min Read
Cognisetin Gains U.S. Patent as Memory Enhancement

IRVINE, Calif.Cyvex Nutritions branded cognitive health ingredient Cognisetin received a Notice of Allowance (NOA) for a key patent specific to methods of using flavonoids to enhance memory by the U.S. Patent and Trademark Office (USPTO). Cognisetin is a fisetin-based ingredient that was introduced last summer in an exclusive license agreement with the Salk Institute for Biological Studies.

The USPTO issued the NOA to indicate the application, titled Methods of Using Flavonoids to Enhance Memory," is genuinely novel. The patent describes fisetin as a neuroprotector capable of generating neuron cells in the presence of damage, promoting antioxidant synthesis, and reducing overactive brain- and spinal cord-specific immune defenses that contribute to age-related decline and/or conditions.

The resulting patent illustrates Cyvexs commitment to the nutraceutical industry by providing evidence-based ingredients with proven scientific support," said Matt Phillips, president of Cyvex Nutrition. This patent validates Cognisetins status as a genuinely novel ingredient with a clinically-backed cognitive health benefit."

Cognisetin is a fisetin-based ingredient that has been shown to stimulate the signaling pathways that enhance long-term memory. Fisetin, a naturally occurring flavonol found in fruits and vegetables including strawberries, serves as a powerful antioxidant by maintaining mitochondrial function during oxidative stress, and has been shown to efficiently cross the blood brain barrier, thus providing great potential in neuroprotection.

Cyvex Nutrition has provided proprietary, condition-specific ingredients to the nutraceutical industry for more than 25 years. The companys antioxidant portfolio includes BioVin®, BioVin Advanced, Cognisetin and Alfapro Agglomerated. Every Cyvex Nutrition ingredient is guaranteed by the companys exclusive NutriPrint® quality assurance system, which includes identity testing of incoming raw materials through FT-NIR, and third-party certification by independent laboratories for active ingredients, microbiology, heavy metals and pesticide and solvent residue when applicable.

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