February 18, 2010
HAUPPAUGE, NYBio-Botanica has been granted a new patent (US # 7,658,955) for its extract of Pueraria candollei var. mirifica A Shaw. & Suvat. (Puresterol®) and the reduction of wrinkles. The patent covers various aspects of the process of manufacturing the ingredient, including extraction, as well as its uses against skin wrinkles. The patent claims also cover the ingredients phytoestrogen content.
This extract was used in a recent research study that showed phyto-oestrogens in Puresterol® were able to inhibit the growth of breast cancer cells, in-vitro. It also has been shown to be a promising phytoestrogenic and support herb for menopausal women, who can experience a range of undesirable symptoms from hot flashes and night sweats to decreased libido and sex interest. In a Phase III study, funded by an agency of the Thai government (J Med Assoc Thai. 2007;90(9)), Pueraria mirifica demonstrated great promise in helping to offset the discomforts associated with menopause. Another study report (J Med Assoc Thai, 2005;88(S1)) noted the results indicated PM is a potential source of effective phytoestrogens for postmenopausal women.
Additionally, Sayan Sawatsri, MD, working with Emory University Department of Obstetrics and Gynecology, in Atlanta, presented a paper on his yet-unpublished research on Pueraria mirifica, which concluded the extract may support estrogen receptors found in cells, and without negatively affecting other cells. PM may constitute a new class of treatment, safe, low toxicity, showing natural SERMs [selective estrogen receptor modulator] properties, agonist in specific tissues and antagonist in other tissues, in vitro and in vivo models, the researchers concluded.
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