CBD oil and related products are flooding the market. In 2018, hemp-based CBD U.S. sales totaled $390 million, but the CBD market size has been estimated to reach anywhere from $1.5 billion to $22 billion by 2022. Although the 2018 Farm Bill removed hemp from the Controlled Substances Act (CSA) and treated the crop as an agricultural commodity subject to USDA’s oversight, FDA has yet to establish a legal pathway to use CBD in food and dietary supplements.