The relationship between research and sales is symbiotic, as the increase in positive study results boosted herbal sales, which then drove new efforts of scientific investigation. The end result is a stream of discoveries that promise to change health in real ways. This Digital Issue explores recent research results for top-selling herbal ingredients, such as cranberry, saw palmetto, ginkgo and curcumin, with additional features on the ever-growing botanical market and new botanical drug business opportunities. Takeaways include: *Promising research is emerging for cranberry, saw palmetto, flaxseed, ginkgo, ginseng, curcumin and garlic. *In 2013, botanicals achieved their biggest year of growth since the late 1990s with retail sales exceeding $6 billion. *About 25 percent of the prescription drugs sold contain active ingredients derived from plants.