Report: Specialized Pro-Resolving Lipid Mediators

Research is revealing many unique and advantageous benefits in specialized pro-resolving mediators (SPMs) such as resolvins, maresins and protectins.

June 12, 2015

1 Min Read
Report: Specialized Pro-Resolving Lipid Mediators

Report Summary

Omega-3s have long been indicated in reducing inflammation throughout the body, potentially aiding conditions such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), vascular inflammation and traumatic brain injury. Recent discoveries point to the use of marine-sourced omega oils to more consciously modulate inflammation resolution in the human body.

Editor's Take

Only in the last decade was it discovered that the regulation of resolution of inflammation is mediated by specific physiological signals. Of particular relevance to the food and dietary supplement ingredient sector, omega-3 fatty acids have been instrumental in this new awareness since they are central to regulating resolution. As research continues, revelation related to omega-3-derived bioactive lipid mediators is at an all-time high.

Takeaways for Your Business

  • Specialized pro-resolving mediators (SPMs) include resolvins, maresins and protectins.

  • Eicosapentaenoic acid, docosahexaenoic acid and arachidonic acid contribute to SPM formation.

  • SPMs actively turn down inflammation through triggering the resolution process.



Nutegrity brings together the expertise of Cyvex Nutrition (botanicals and fish oils), Wisconsin Specialty Protein (dairy ingredients) and InCon Processing (molecular distillation), all subsidiaries of Omega Protein Corporation, to meet the evolving needs of todays health-conscious consumer.

Nutegritys mission is to provide pure, sustainable human nutrition products that support healthy living including a wide range of marine-based omega-3s/EFAs, dairy and plant protein products, specialty dairy ingredients, and botanically sourced ingredients for use in functional food and beverage applications.

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