A new clinical study was recently published in Aging Male on Testofen®, a proprietary fenugreek seed extract from Gencor.

The 12-week study was a double-blind, randomized, placebo-controlled trial involving 120 healthy men between the ages of 43 and 70. Conducted in Brisbane, Australia, the trial examined the effect of the herbal ingredient Testofen on the symptoms of possible androgen deficiency, sexual function and serum androgen concentrations in healthy aging males.

The primary outcome measure was efficacy of treatment for symptoms using the Aging Male Symptom questionnaire (AMS), which consists of 17 questions in three sub-scales: psychological, somatic and sexual.  Secondary outcome measures were sexual function—assessed using the Derogatis Interview for Sexual Functioning-Self Report (DISF-SR) questionnaire—and serum sex hormone concentrations.

The results showed a significant decrease in AMS score over time and between the active and placebo groups, indicating a greater reduction in symptom severity in the active group compared with the placebo. Sexual function significantly improved in the active group, including the number of morning erections and the frequency of sexual activity. Both total serum testosterone and free testosterone increased in the active compared to placebo after 12 weeks of active treatment.

The study suggested Testofen was effective in reducing symptoms of possible androgen deficiency, improving sexual function, and increasing serum testosterone in healthy middle-aged and older men.