Natural Products Insider is part of the Informa Markets Division of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC's registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

Vitamin B12 effective for eczema

Vitamin B12 effective for eczema.jpg
Topical vitamin B12 has been shown to help relieve duration and severity of atopic dermatitis, aka eczema.

BOCHUM, Germany - Topical vitamin B12 helps relieve the severity and duration of atopic dermatitis, according to a study published in the British Journal of Dermatology (150, 5:977-83 May 2004) ( Researchers from Ruhr University, Bochum, evaluated the efficacy and tolerability of topical vitamin B12 and its effects on atopic dermatitis--also known as eczema.


The prospective, randomized, placebo-controlled, phase III, multicenter, clinical trial treated 49 patients for eight weeks. Each patient applied the vitamin B12-containing active preparation twice daily to affected skin areas of one side of the body and a placebo preparation to the other side, according to a randomization scheme.

On the side treated with the vitamin B12 cream, the modified Six Area, Six Sign, Atopic Dermatitis score (SEM) dropped to a significantly greater extent than that of the placebo-treated side (5534 SEM versus 2887 SEM for B12 and placebo, respectively).

The scientists concluded topical vitamin B12 cream, as a new therapeutic approach in atopic dermatitis, may be effective in the reduced extent and severity of atopic dermatitis.


Hide comments


  • Allowed HTML tags: <em> <strong> <blockquote> <br> <p>

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.