Meso-Zeaxanthin Aids Eyes

MIAMI—A supplement of meso-zeaxanthin may bolster macular pigment optical density (MPOD), according to researchers from Florida International University (Nutr Metab. 2007;4:12) (DOI:10.1186/1743-7075-4-12). Lutein and zeaxanthin have been the primary focus of research trials exploring how the xanthophyll carotenoids can support macular pigment and possibly prevent onset of age-related macular degeneration (AMD). Meso-zeaxanthin is the third major carotenoid found in macular pigment.

In this 120-day supplementation study, 10 subjects received gelcaps containing 20 mg/d of predominantly meso-zeaxanthin, with smaller amounts of lutein and zeaxanthin; 9 additional subjects formed a control group taking a placebo. Supplementation increased blood serum levels of all three carotenoids during the supplementation period. In addition, MPOD, measured at 460 nm, rose at an average rate of 0.59 ± 0.79 milli-absorbance unit/day in the 10 supplemented subjects; no such change was seen in the placebo group. These trial results showed meso-zeaxanthin was absorbed into the serum following supplementation and was effective at raising MPOD.

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