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CoQ10 Bioavailability, Formulation (Co-operation, Competition in the CoQ10 Market)

Heather Granato
04/17/2008
Continued from page 4

References

1. Singh RB et al. "Effect of coenzyme Q10 on experimental atherosclerosis and chemical composition and quality of atheroma in rabbits." Atherosclerosis. 2000;148(2):275-82.

2.Singh RB et al. "Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction." Mol Cell Biochem. 2003;246(1-2):75-82.

3. Thomas SR et al. "Dietary cosupplementation with vitamin E and coenzyme Q(10) inhibits atherosclerosis in apolipoprotein E gene knockout mice." Arterioscler Thromb Vasc Biol. 2001;21(4):585-93.

4. Rosenfeldt F et al. "Systematic review of effect of coenzyme Q10 in physical exercise, hypertension and heart failure." Biofactors. 2003;18(1-4):91-100.

5. Houston MC. "The role of vascular biology, nutrition and nutraceuticals in the prevention and treatment of hypertension." JANA. S1:5-71, 2002.

6. Littarru GP, Langsjoen P. “Coenzyme Q10 and statins: biochemical and clinical implications.” Mitochondrion. 2007 Jun;7 Suppl:S168-74.

7. Kawashiri MA et al. “Comparison of Effects of Pitavastatin and Atorvastatin on Plasma Coenzyme Q10 in Heterozygous Familial Hypercholesterolemia: Results from a Crossover Study.” Clin Pharmacol Ther. 2007 Oct 24; ePub ahead of print.

8. Passi S et al. “Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA.” Biofactors. 2003;18(1-4):113-24.

9. Gullestad L et al. “The role of statins in heart failure.” Fundam Clin Pharmacol. 2007 Nov;21 Suppl 2:35-40.

10. Willis R et al. "Clinical implications of the correlation between coenzyme Q10 and vitamin B6 status." Biofactors. 1999;9(2-4):359-63.

11. Joseph JA, et al “Reversals of Age-Related Declines in Neuronal Signal Transduction, Cognitive, and Motor Behavioral Deficits with Blueberry, Spinach, or Strawberry Dietary Supplementation.” J Neurosci. 1999;19:8114-8121.

12. Moreira PI et al. "CoQ10 therapy attenuates amyloid beta-peptide toxicity in brain mitochondria isolated from aged diabetic rats." Exp Neurol. 2005;196(1):112-9.

13.Li G, Zou L, “Neuroprotective effect of Coenzyme Q10 on ischemic hemisphere in aged mice with mutations in the amyloid precursor protein” Neurobiol Aging. 2007;28(6):877-82.

14. Cleren C et al. “Therapeuticl effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism.” J Neurochem. 2008 Mar;104(6):1613-21.

15. Murata T, Ohtsuka C, Terayama Y. “Increased mitochondrial oxidative damage and oxidative DNA damage contributes to the neurodegenerative process in sporadic amyotrophic lateral sclerosis.” Free Radic Res. 2008 Mar;42(3):221-5.

16. Mizuno K et al. “Antifatigue effects of coenzyme Q10 during physical fatigue.” Nutrition. 2008 Apr;24(4):293-299.

17. Kon M et al. “Reducing exercise-induced muscular injury in kendo athletes with supplementation of coenzyme Q10.” Br J Nutr. 2008 Feb 20;1-7.

18. Cooke M et al. “Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals.” J Int Soc Sports Nutr. 2008 Mar 4;5(1):8.

19. Ikematsu H et al. “Safety assessment of coenzyme Q10 (Kaneka Q10) in healthy subjects: A double-blind, randomized, placebo-controlled trial.” Regul Toxicol Pharmacol. 2006;44:21218.

20. Hosoe K et al. “Study on safety and bioavailability of ubiquinol (Kaneka QH™) after single and 4-week multiple oral administration to healthy volunteers.” Regul Toxicol Pharmacol. 2007;47:19-28.

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