Cognitive and Memory Preservation

References for "Cognitive and Memory Preservation"

1. Markesbery WR and Lovell MA. "Damage to lipids, proteins, DNA, and RNA in mild cognitive impairment." Arch Neurol. 2007 Jul;64(7):954-6.

2. Lau FC et al. "The beneficial effects of fruit polyphenols on brain aging." Neurobiol Aging. 2005;26, Suppl 1:128-32.

3. Rinaldi P et al. "Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease." Neurobiol Aging  2003;24, 7:915-9.

4. Sen et al., “Vitamin E sensitive genes in the developing rat fetal brain : a high density oligonucleotide microarray analysis” FEBS Letter. 2002;530:17-23.

5. Young, AJ, et al. “Coenzyme Q10: a review of its promise as a neuroprotectant” CNS Spectr. 2007;12,1:62-8.  

6. Moreira PI et al. "CoQ10 therapy attenuates amyloid beta-peptide toxicity in brain mitochondria isolated from aged diabetic rats." Exp Neurol. 2005;196, 1:112-9.

7. McDonald SR et al. "Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice." Free Radic Biol Med. 2005;38, 6:729-36.

8. Kumar, P., “Possible neuroprotective mechanisms of curcumin in attenuating 3-nitropropionic acid-induced neurotoxicity”  Exp Clin Pharmacol. 2007;29,1:19-25.

9. Zhang L, et al. “Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer's disease patients”J Alzheimer’s Dis. 2006;10, 1:1-7. 

10. Ryan J et al. " An examination of the effects of the antioxidant Pycnogenol on cognitive performance, serum lipid profile, endocrinological and oxidative stress biomarkers in an elderly population." J Psychopharmacol. 2008 Jul;22(5):553-62.

11. Trebaticka J et al. "Treatment of ADHD with French maritime pine bark extract, Pycnogenol." Eur Child Adolesc Psychiatry. 2006 Sep;15(6):329-35.

12. Silberstein RB et al. "Improved cognitive performance after dietary supplementation with a Pinus radiata bark extract Formulation." Phytotherapy Research. 2008; 22(9):1168-74.

13. Walesiuk A et al. "Ginkgo biloba normalizes stress- and corticosterone-induced impairment of recall in rats." Pharmacol Res. 2006;53, 2:123-8.

14. Walesiuk A et al “Preventive action of Ginkgo biloba in stress- and corticosterone-induced impairment of spatial memory in rats” Phytomedicine, May 3, 2007; ePub ahead of print.

15. Wang Y et al. "The in vivo synaptic plasticity mechanism of EGb 761-induced enhancement of spatial learning and memory in aged rats." Br J Pharmacol. 2006;148, 2:147-53.

16. Zhang M et al. "Extract of Ginkgo biloba leaves reverses yohimbine-induced spatial working memory deficit in rats." Behav Pharmacol. 2005;16, 8:651-6.

17. Dodge HH et al. " A randomized placebo-controlled trial of Ginkgo biloba for the prevention of cognitive decline." Neurology. 2008 May 6;70(19 Pt 2):1809-17.

18.  Presented at 55th Inter-national Congress of the Society for Medical Plant Research in Graz, Austria, September 2007.

19. Proprietary study. Frutarom.com

20. Proprietary study. Frutarom.com

21. Hagiwara, M., Endo, Y., Hidaka, H., "Effects of vinpocetine on cyclic nucleotide

metabolism in vascular smooth muscle" Biochem Pharmacol 1984;33:453-457.

22. Schmid-Schonbein H et al. "Restoration of microsieve filterability of human red cells after exposure to hyperosmolarity and lactacidosis: Effect of Vinpocetine", Drug Development Research, 1988;14, 205-211.

23. Subhan Z and I. Hindmarch, "Psychopharmacogical Effects of Vinpocetine in Normal Healthy Volunteers", Eur. J. Clin. Pharmacol. 1985;28, 567-571.

24. Sitges M et al. " Vinpocetine prevents 4-aminopyridine-induced changes in the EEG, the auditory brainstem responses and hearing." Clin Neurophysiol. 2004 Dec;115(12):2711-7.

25. Helland IB et al. "Maternal supplementation with very-long-chain n-3 fatty acids during pregnancy and lactation augments children's IQ at 4 years of age." Pediatrics. 2003;111(1):e39-44.

26. Birch EE et al. " Visual acuity and cognitive outcomes at 4 years of age in a double-blind, randomized trial of long-chain polyunsaturated fatty acid-supplemented infant formula." Early Hum Dev. 2007 May;83(5):279-84.

27. Innis SM. " Dietary omega 3 fatty acids and the developing brain." Brain Res. 2008 Sep 9. Epub ahead of print.

28. Whalley LJ, et al. “Cognitive aging, childhood intelligence, and the use of food supplements: possible involvement of n-3 fatty acids” AJCN 2004;80,6:1650-57.

29. Barberger-Gateau P, et al. “Fish, meat, and risk of dementia: cohort study” BMJ. 2002;325:932-3.

30. Freund-Levi Y et al “Omega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study: a randomized double-blind trial” Archives of Neurology 2006;63,10:1402-8.

31. Floernt-Bechard S et al. " Towards a nutritional approach for prevention of Alzheimer's disease: biochemical and cellular aspects." J Neurol Sci. 2007 Nov 15;262(1-2):27-36.

32. Farooqui AA et al. "Modulation of inflammation in brain: a matter of fat." J Neurochem. 2007;101(3):577-99.

33. Guo M et al. " Neuronal specific increase of phosphatidylserine by docosahexaenoic acid." J Mol Neurosci. 2007 Sep;33(1):67-73.

34. Salem N et al. "Mechanisms of action of docosahexaenoic acid in the nervous system." Lipids. 2001 Sep;36(9):945-59.

35. Thal LJ et al. “A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer’s disease” Neurology 1996;47:705-711.

36. Jorissen BL et al. " The influence of soy-derived phosphatidylserine on cognition in age-associated memory impairment." Nutr Neurosci. 2001;4(2):121-34.

37. Recently closed trial. Sourasky, Tel-Aviv Medical Center, Israel. Enzymotec.com

38. Parnetti L et al. "Cholinergic precursors in the treatment of cognitive impairment of vascular origin: ineffective approaches or need for re-evaluation?" J Neurol Sci. 2007 Jun 15;257(1-2):264-9.

39. Amenta F et al. "Association with the cholinergic precursor choline alphoscerate and the cholinesterase inhibitor rivastigmine: an approach for enhancing cholinergic neurotransmission." Mech Ageing Dev. 2006 Feb;127(2):173-9.

40. Tomassoni D et al. "Effect of treatment with choline alphoscerate on hippocampus microanatomy and glial reaction in spontaneously hypertensive rats." Brain Res. 2006 Nov 20;1120(1):183-90.

41. Parnetti L et al. "Choline alphoscerate in cognitive decline and in acute cerebrovascular disease: an analysis of published clinical data." Mech Ageing Dev. 2001 Nov;122(16):2041-55.

42. DeJesus Moreno M. "Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial." Clin Ther. 2003 Jan;25(1):178-93.

43. Fioravanti M et al. "Cytidinediphosphocholine CDP-choline for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly." Cochrane Database Syst Rev. 2:CD000269, 2005.

44. Citicoline Monograph. Alt Med Rev. 2008;13(1):51-7.

45. Babb SM, Appelmans KE, Renshaw PF, et al. “Differently effect of CDP-choline on brain cytosolic choline levels in younger and older subjects as measured by magnetic resonance spectroscopy.” Psychopharmacology 1996;127:88-94.

46. Chung SY et al. " Administration of phosphatidylcholine increases brain acetylcholine concentration and improves memory in mice with dementia. " J Nutr. 1995 Jun;125(6):1484-9.

47. Alvarez XA et al. “Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion” Methods Find Exp Clin Pharmacol. 1999;21(9):633-44.

48. Secades JJ and Lorenzo JL. " Citicoline: pharmacological and clinical review, 2006 update." Methods Find Exp Clin Pharmacol. 2006 Sep;28 Suppl B:1-56.

49. Alvarez XA et al. “Citicoline improves memory performance in elderly subjects” Methods  Find Exp Clin Pharmacol. 1997;19(3):201-10.

50. Teather LA and Wurtman RJ. "Dietary CDP-choline supplementation prevents memory impairment caused by impoverished environmental conditions in rats." Learn Mem. 2005 Jan-Feb;12(1):39-43.

51. Kronenberg G et al. " Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase." J Neurosci. 2008 Jul 9;28(28):7219-30.

52. Connelly PJ et al. " A randomised double-blind placebo-controlled trial of folic acid supplementation of cholinesterase inhibitors in Alzheimer's disease." Int J Geriatr Psychiatry. 2008 Feb;23(2):155-60.

53. Durga J et al. " Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial." Lancet. 2007 Jan 20;369(9557):208-16.

54. Tettamanti M et al. " Low folate and the risk of cognitive and functional deficits in the very old: the Monzino 80-plus study." J Am Coll Nutr. 2006 Dec;25(6):502-8.

55. Das UN. "Folic acid and polyunsaturated fatty acids improve cognitive function and prevent depression, dementia, and Alzheimer's disease--but how and why?" Prostaglandins Leukot Essent Fatty Acids. 2008 Jan;78(1):11-9.

56. Wahlin A et al. “Vitamin B status and cognitive performance in preclinical and clinical Alzheimer's disease: data from the Kungsholmen Project” Dement Geriatr Cogn Disord. 2008;25(1):23-31.

57. Sun Y et at. “Efficacy of multivitamin supplementation containing vitamins B6 and B12 and folic acid as adjunctive treatment with a cholinesterase inhibitor in Alzheimer's disease: a 26-week, randomized, double-blind, placebo-controlled study in Taiwanese patients” Clin Ther. 2007;29(10):2204-14.

58. Puri V et al. " Vitamin B12 deficiency: a clinical and electrophysiological profile."

Electromyogr Clin Neurophysiol. 2005 Jul-Aug;45(5):273-84.

59. Refsum H et al. "Vitamin B12 status and rate of brain volume loss in community-dwelling elderly." Neurology. 2008 Sep 9;71(11):826-32.

60. Smith AD. "The worldwide challenge of the dementias: a role for B vitamins and homocysteine?" Food Nutr Bull. 2008 Jun;29(2 Suppl):S143-72.