Developing Blood Circulation Products

Niacin is commonly used in blood circulation formulas because of its effect on increasing blood flow to the periphery. There is substantial research showing 3 g/d niacin can help lower cholesterol. Individuals who take large doses of niacin should be under the care of a health care practitioner because of the adverse effects. It has been suggested that 50 to 100 mg of niacin can cause flushing, nausea and gastrointestinal upset. Time-release niacin appears to be helpful in reducing skin flushing; however, there have been reports of liver problems associated with this form.

Blood circulation products can be quite successful when a product developer does a thorough investigation of ingredients to support blood flow and blood vessels. There are various nutrients worthwhile adding to a blood circulation formula, it just takes time and diligence in the investigation process

Judi Quilici-Timmcke, M.S., is president of Q-Tech Services Inc. (JudiQ.com), a product formulation firm in the dietary supplement industry. She holds a master’s degree in dietetics/exercise physiology, and has worked previously as vice president of product development and research for Weider Nutrition- Specialty Market and as director of product development and research for Rexall Showcase International.

Bibliography

• Blumenthal M et al, eds. The Complete Commission E Monographs, Therapeutic Guide to Herbal Medicines. Boston: Integrative Medicine Communications. 1998;136-138.
• Garg R et al. “Niacin treatment increases plasma homocysteine levels.” Am Heart J. 1999;138:1082-1087.
• Goldberg A et al. “Multiple-dose efficacy and safety of an extended-release form of niacin in the management of hyperlipidemia.” Am J Cardiol. 2000;85:1100-1105.
• Knopp RH. “Niacin and hepatic failure.” Ann Intern Med. 1989;111:769..
• Kohls KJ, Kies C, Fox HM. “Serum lipid levels of humans given arginine, lysine and tryptophan supplements without food.” Nutr Rep Int. 1987;35:5-13.
• Rahman K, Billington D. “Dietary Supplementation with Aged Garlic Extract Inhibits ADP-Induced Platelet Aggregation in Humans.” J Nutr. 2000;130:2662-2665.
• Schulman SP et al. “L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction randomized clinical trial.” JAMA. 2006;295:58-64.
• Welsh AL, Ede M. “Inositol hexanicotinate for improved nicotinic acid therapy.” Int Record Med. 1961;174:9-15.
• Wolf A et al. “Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans.” J Am Coll Cardiol. 1997;29:479-85.

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