MILAN, ItalyTomato carotenoids modulate inflammatory markers,
according to new research from the University of Milan (J Agric Food Chem,
54, 7:2563-6, 2006).
Researchers investigated the effects of a tomato-based drink (as
Lyc-O-MatoŽ, from LycoRed Ltd. [www.lycored.com]), on inflammatory markers (by
enzyme immunoassay) and other end points in 26 healthy young volunteers, in a
placebo-controlled, double blind, crossover fashion.Test subjects received
Lyc-O-Mato (5.7 mg of lycopene, 3.7 mg of phytoene, 2.7 mg of phytofluene, 1 mg
of betacarotene, and 1.8 mg of alpha-tocopherol) and a placebo drink (same taste
and flavor, but devoid of active compounds) for 26 days, separated by a wash-out
period. During the study subjects maintained their normal diets. Production of
the inflammatory marker tumor necrosis factor-alpha (TNF-a) by whole blood was
34.4-percent lower after 26 days of Lyc-o-Mato intake.