D-Ribose Boosts Energy

BOCA RATON, Fla.—Ribose, a naturally occurring pentose carbohydrate and component of the energy molecule adenosine triphosphate (ATP), enhances high-energy phosphates and improves diastolic dysfunction following myocardial ischemia, according to new research presented at a meeting of the Heart Failure Society of America.

In the two-center study, researchers administered 5g/d ribose (as CORvalen, from Bioenergy) to 23 congestive heart failure (CHF) patients ranked in New York Heart Association (NYHA) Classes II-IV. Cardiopulmonary exercise tests using a four-minute sub-maximal step protocol were completed and a retrospective analysis was performed after the eight-week routine clinical visit.Ventilatory efficiency (Veff) was assessed up to the anaerobic threshold at baseline and after eight weeks of ribose supplementation.

D-ribose significantly improved Veff in patient Classes III and IV, with a trend towards improvement in Class II patients. Oxygen uptake efficiency demonstrated a strong trend in Classes III and IV.

“As cardiologists know, CHF patients have decreased levels of myocardial high-energy compounds contributing to myocardial dysfunction,” said John St. Cyr, M.D., Ph.D., medical director for Bioenergy Inc., which helped organize the study. “Further, advanced class CHF patients have compromised oxygen utilization efficiency, or Veff, as it is often referred to. This limits their exercise reserve even during sub-maximal exertion. After using D-ribose for eight weeks the patients in this study demonstrated a significant improvement in Veff, the most powerful predictor of survival in CHF patients.”

For more information, visit www.bioenergy.com or Booth #4101- 4103 at SupplySide West.

Share this article: Email, Slashdot, Digg, Del.icio.us, Yahoo!MyWeb, Windows Live Favorites, Furl
Add this article feed to: RSS, My Yahoo, Newsgator, Bloglines