Cancer References

Sept. 13, 2004 - Natural Products Industry INSIDER
"Cancer" References

1. Keck AS, Finley JW. "Cruciferous vegetables: cancer protective mechanisms of glucosinolate hydrolysis products and selenium." Integr Cancer Ther. 3, 1:5-12, 2004.

2. Johnson IT. "New approaches to the role of diet in the prevention of cancers of the alimentary tract." Mut Res. 551, 1-2:9-28, 2004. www.mutationresearch.com

3. Hara M et al. "Cruciferous vegetables, mushrooms and gastrointestinal cancer risks in a multicenter, hospital-based case-control study in Japan." Nutr Cancer. 46, 2:138-47, 2003. www.erlbaum.com/Journals/journals/NC/nc.htm

4. Hu J et al. "Diet and vitamin or mineral supplements and risk of renal cell carcinoma in Canada." Cancer Causes Control. 14, 8:705-14, 2003. www.kluweronline.com/issn/0957-5243/contents

5. Klaunig JE, Kamendulis LM. "The role of oxidative stress in carcinogenesis." Annu Rev Pharmacol Toxicol. 44:239-67, 2004. http://nutr.annualreviews.org/

6. Moller P, Loft S. "Interventions with antioxidants and nutrients in relation to oxidative DNA damage and repair." Mut Res. 551, 1-2:79-89, 2004. www.mutationresearch.com

7. Seifried HE et al. "The antioxidant conundrum in cancer." Cancer Res. 63, 15:4295-8, 2003. http://cancerres.aacrjournals.org

8. Prasad KN. "Antioxidants in cancer care: when and how to use them as an adjunct to standard and experimental therapies." Expert Rev Anticancer Ther. 3, 6:903-15, 2003.

9. Mantovani G et al. "The impact of different antioxidant agents alone or in combination on reactive oxygen species, antioxidant enzymes and cytokines in a series of advanced cancer patients at different sites: correlation with disease progression." Free Rad Res. 37, 2:213-23, 2003. www.tandf.co.uk/journals

10. Drisko JA, Chapman J, Hunter VJ. "The use of antioxidants with first-line chemotherapy in two cases of ovarian cancer." J Am Coll Nutr. 22, 2:118-23, 2003. www.am-coll-nutr.org/jacn/jacn.htm

11. Block KI, Mead MN. "Vitamin C in alternative cancer treatment: historical background." Integr Cancer Ther. 2, 2:147-54, 2003.

12. Wenzel U et al. "Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions." Carcinogenesis. 25, 5:703-12, 2004. http://carcin.oupjournals.org

13. Nissen SB et al. "Intake of vitamins A, C and E from diet and supplements and breast cancer in postmenopausal women." Cancer Causes Control. 14, 8:695-704, 2003. www.kluweronline.com/issn/0957-5243/contents

14. Gunawardena K, Campbell LD, Meikle AW. "Combination therapy with vitamins C plus E inhibits survivin and human prostate cancer cell growth." Prostate. 59, 3:319-27, 2004.

15. Fleischauer AT, Simonsen N, Arab L. "Antioxidant supplements and risk of breast cancer recurrence and breast cancer-related mortality among postmenopausal women." Nutr Cancer. 46, 1:15-22, 2003. www.erlbaum.com/Journals/journals/NC/nc.htm

16. Sung L et al. "Vitamin E: the evidence for multiple roles in cancer." Nutr Cancer. 46, 1:1-14, 2003. www.erlbaum.com/Journals/journals/NC/nc.htm

17. Campbell S et al. "Development of gamma (gamma)-tocopherol as a colorectal cancer chemopreventive agent." Crit Rev Oncol Hematol. 47, 3:249-59, 2003.

18. Huang HY et al. Prospective study of antioxidant micronutrients in the blood and the risk of developing prostate cancer. Am J Epidemiol. 175, 4:335-44, 2003. www.aje.oupjournals.org.

19. Virtamo J et al. "Incidence of cancer and mortality following alpha-tocopherol and beta-carotene supplementation: a postintervention follow-up." JAMA. 290, 4:476-85, 2003. www.jama.com

20. Rodriguez C et al. "Vitamin E supplements and risk of prostate cancer in U.S. men." Cancer Epidemiol Biomarkers Prev. 13, 3:378-82, 2004. http://cebp.aacrjournals.org/

21. Takagi H et al. "Pilot clinical trial of the use of alpha-tocopherol for the prevention of hepatocellular carcinoma in patients with liver cirrhosis." Int J Vitam Nutr Res. 73, 6:411-5, 2003.

22. Jacobs EJ et al. "Vitamin C and vitamin E supplement use and bladder cancer mortality in a large cohort of U.S. men and women." Am J Epidemiol. 156, 11:1002-10, 2002. www.aje.oupjournals.org.

23. Taylor PR et al. "Prospective study of serum vitamin E levels and esophageal and gastric cancers." J Natl Cancer Inst. 95, 18:1414-6, 2003. http://jncicancerspectrum.oupjournals.org/jnci.

24. Neuzil J. "Vitamin E succinate and cancer treatment: a vitamin E prototype for selective antitumor activity." Br J Cancer. 89, 10:1822-6, 2003. www.nature.com/bjc

25. Dalen H, Neuzil J. "Alpha-tocopheryl succinate sensitizes a T lymphoma cell line to TRAIL-induced apoptosis by suppressing NF-kappaB activation." Br J Cancer. 88, 1:153-8, 2003. www.nature.com/bjc

26. Shun MC et al. "Pro-apoptotic mechanisms of action of a novel vitamin E analog (alpha-TEA) and a naturally occurring form of vitamin E (delta-tocotrienol) in MDA-MB-435 human breast cancer cells." Nutr Cancer. 48, 1:95-105, 2004. www.erlbaum.com/Journals/journals/NC/nc.htm

27. McIntyre BS et al. "Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells." Proc Soc Exp Biol Med. 224:292-301, 2002.

28. Guthrie N et al. Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination. J Nutr. 127, 3:544S-548S, 1997. www.nutrition.org.

29. Venkateswaren V, Fleshner NE, Klotz LH. "Synergistic effect of vitamin E and selenium in human prostate cancer cell lines." Prostate Cancer Prostatic Dis. 7, 1:54-6, 2004.

30. Li H. "A prospective study of plasma selenium levels and prostate cancer risk." J Natl Cancer Inst. 96, 9:696-703, 2004. http://jncicancerspectrum.oupjournals.org/jnci.

31. Duffield-Lillico AJ et al. Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial. BJU Int. 91, 7:608-12, 2003.

32. Whanger PD. "Selenium and its relationship to cancer: an update dagger." Br J Nutr. 91, 1:11-28, 2004. www.cabi-publishing.org/journals/bjn

33. Waters DJ et al. "Making sense of sex and supplements: differences in the anticarcinogenic effects of selenium in men and women." Mut Res. 551, 1-2:91-107, 2004. www.mutationresearch.com

34. Moyad MA. "Zinc for prostate disease and other conditions: a little evidence, a lot of hype and a significant potential problem." Urol Nurs. 24, 1:49-52, 2004. www.ahsl.arizona.edu/journals/ejrnl_gateway.cfm?name=Urologic%20Nursing

35. Costello LC et al. "Role of zinc in the pathogenesis and treatment of prostate cancer: critical issues to resolve." Prostate Cancer Prostat Dis. 7, 2:111-7, 2004.

36. Feng P et al. "Effect of zinc on prostatic tumorigenicity in nude mice." Ann NY Acad Sci. 1010:316-20, 2003. www.nyas.org/publications/annals/

37. Stover PJ. "Physiology of folate and vitamin B12 in health and disease." Nutr Rev. 62, 6 Pt. 2:S3-12, 2004. www.ilsi.org/publications/reviews.html

38. Kim YI. "Folate, colorectal carcinogenesis and DNA methylation: lessons from animal studies." Environ Mol Mutagen. 44, 1:10-25, 2004.

39. Choi SW et al. "Vitamin B-12 deficiency induces anomalies of base substitution and methylation in the DNA of rat colonic epithelium." J Nutr. 134, 4:750-5, 2004. www.nutrition.org

40. Zhang SM. "Role of vitamins in the risk, prevention and treatment of breast cancer." Curr Opin Obstet Gynecol. 16, 1:19-25, 2004. www.co-obgyn.com

41. Sellers TA et al. "Dietary folate intake, alcohol and risk of breast cancer in a prospective study of postmenopausal women." Epidemiology. 12, 4:420-8, 2001. www.epidem.com

42. Hernandez BY et al. "Diet and premalignant lesions of the cervix: evidence of a protective role for folate, riboflavin, thiamin and vitamin B12." Cancer Causes Control. 14, 9:859-70, 2003. www.kluweronline.com/issn/0957-5243/contents

43. Chew BP, Park JS. "Carotenoid action on the immune response." J Nutr. 134, 1:257S-61S, 2004. www.nutrition.org

44. Castelao JE et al. "Carotenoids/vitamin C and smoking-related bladder cancer." Int J Cancer. 110, 3:417-23, 2004. www3.interscience.wiley.com

45. Nkondjock A, Ghadirian P. "Dietary carotenoids and the risk of colon cancer: case-control study." Int J Cancer. 110, 1:110-6, 2004. www3.interscience.wiley.com

46. Wu K et al. "Plasma and dietary carotenoids, and the risk of prostate cancer: a nested case-control study." Cancer Epidemiol Biomarkers Prev. 13, 2:260-9, 2004. http://cebp.aacrjournals.org/

47. Binns CW, LJ LJ, Lee AH. "The relationship between dietary carotenoids and prostate cancer risk in Southeast Chinese men." Asia Pac J Clin Nutr. 13, Suppl:S117, 2004.

48. Etminan M, Takkouche B, Caamano-Isorna F. "The role of tomato products and lycopene in the prevention of prostate cancer: a meta-analysis of observational studies." Cancer Epidemiol Biomarkers Prev. 13, 3:340-5, 2004. http://cebp.aacrjournals.org/

49. Hwang ES, Bowen PE. "Can the consumption of tomatoes or lycopene reduce cancer risk?" Integr Cancer Ther. 1, 2:121-32, 2002.

50. Kucuk O et al. Effects of lycopene supplementation in patients with localized prostate cancer. Exp Biol Med (Maywood). 227, 10:881-5, 2002. www.ebmonline.org.

51. Nishino H et al. American Academy of Cancer Research.

52. Jyonouchi H et al. "Antitumor activity of astaxanthin and its mode of action." Nutr Cancer. 36, 1:59-65, 2000. www.erlbaum.com/Journals/journals/NC/nc.htm

53. Kurihara H et al. "Contribution of the antioxidative property of astaxanthin to its protective effect on the promotion of cancer metastasis in mice treated with restraint stress." Life Sci. 70, 21:2509-20, 2002. www.sciencedirect.com/science/journal/00243205

54. Paolini M et al. Beta-carotene: a cancer chemopreventive agent or a co-carcinogen? Mut Res. 543, 3:195-200, 2003. www.mutationresearch.com.

55. Baron JA et al. "Neoplastic and antineoplastic effects of beta-carotene on colorectal adenoma recurrence: results of a randomized trial." J Natl Cancer Inst. 95, 10:717-22, 2003. http://jncicancerspectrum.oupjournals.org/jnci.

56. Palozza P et al. Beta-carotene regulates NF-kappaB DNA-binding activity by a redox mechanism in human leukemia and colon adenocarcinoma cells. J Nutr. 133, 2:381-8, 2003. www.nutrition.org.

57. Jones DJ et al. "Characterization of metabolites and the putative cancer chemopreventive agent quercetin and their effect on cyclo-oxygenase activity." Br J Cancer. Epub ahead of print; Aug. 3, 2004. www.nature.com/bjc

58. Indap MA, Barkume MS. "Efficacies of plant phenolic compounds on sodium butyrate induced anti-tumour activity." Indian J Exp Biol. 41, 8:861-4, 2003.

59. Wildman RE (ed). Handbook of Nutraceuticals and Functional Foods. 113-26, 2001. CRC Press.

60. Manthey JA, Guthrie N. "Antiproliferative activities of citrus flavonoids against six human cancer cell lines." J Agric Food Chem. 50:5837-43, 2002. http://pubs.acs.org/journals/jafcau

61. Manthey JA, Guthrie N, Grohmann K. "Biological properties of citrus flavonoids pertaining to cancer and inflammation." Curr Medicinal Chem. 8:135-53, 2001.

62. Guthrie N et al. "Inhibition of human breast cancer cells by citrus limonoids." ACS Symposium Series, 2000.

63. Bagchi D et al. "Anti-angiogenic, antioxidant and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula." Biochemistry (Mosc). 69, 1:75-80, 2004.

64. Roy S et al. "Anti-angiogenic property of edible berries." Free Rad Res. 36, 9:1023-31, 2002. www.tandf.co.uk/journals

65. Singh RP et al. "Grape seed extract inhibits advanced human prostate tumor growth and angiogenesis and upregulates insulin-like growth factor binding protein-3." Int J Cancer. 108, 5:733-40, 2004. www3.interscience.wiley.com

66. Agarwal C, Singh RP, Agarwal R. "Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c release." Carcinogenesis. 23, 11:1869-76, 2002. http://carcin.oupjournals.org

67. Dhanalakshmi S, Agarwal R, Agarwal C. "Inhibition of NF-kappaB pathway in grape seed extract-induced apoptotic death of human prostate carcinoma DU145 cells." Int J Oncol. 23, 3:721-7, 2003. www.erlbaum.com/Journals/journals/NC/nc.htm

68. Tyagi A, Agarwal R, Agarwal C. "Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis." Oncogene. 22, 9:1302-16, 2003.

69. Cheng Y et al. "Inhibition of nicotine-DNA adduct formation in mice by six dietary constituents." Food Chem Tox. 41, 7:1045-50, 2003. www.elsevier.nl/locate/foodchemtox

70. Bagchi M et al. "Protective effects of antioxidants against smokeless tobacco-induced oxidative stress and modulation of Bc1-2 and p53 genes in human oral keratinocytes." Free Rad Res. 35, 2:181-94, 2001. www.tandf.co.uk/journals

71. Stewart JR, Artime MC, O'Brian CA. "Resveratrol: a candidate nutritional substance for prostate cancer prevention." J Nutr. 133, 7 Suppl:2440S-43S, 2003. www.nutrition.org

72. Fu ZD et al. "[Chemopreventive effect of reseveratrol to cancer.]" Ai Zheng. 23, 8:869-73, 2004.

73. Schneider Y et al. "(Z)-3,5,4'-Tri-O-methyl-resveratrol induces apoptosis in human lymphoblastoid cells independently of their p53 status." Cancer Lett. 211, 2:155-61, 2004. www.elsevier.com/locate/canlet

74. Zhou HB et al. "Resveratrol induces apoptosis in human esophageal carcinoma cells." World J Gastroenterol. 9, 3:408-11, 2003.

75. Huynh HT, Teel RW. "Selective induction of apoptosis in human mammary cancer cells (MCF-7) by Pycnogenol." Anticancer Res. 20, 4:2417-20, 2000. www.geocities.com/Athens/Rhodes/8729/iiar/iiar.htm

76. Peng Q, Wei Z, Lau BH. "Pycnogenol inhibits tumor necrosis factor-alpha-induced nuclear factor kappa B activation and adhesion molecule expression in human vascular endothelial cells." Cell Mol Life Sci. 57, 5:834-41, 2000.

77. Park OJ, Surh YJ. "Chemopreventive potential of epigallocatechin gallate and genistein: evidence from epidemiological and laboratory studies." Toxicol Lett. 150, 1:43-56, 2004. www.sciencedirect.com/science/journal/03784274

78. Mu LN et al. "[Study on the protective effect of green tea on gastric, liver and esophageal cancers.]" Zhonghua Yu Fang Yi Xue Za Zhi. 37, 3:171-3, 2003.

79. Binns CW et al. "Green tea consumption enhances survival of epithelial ovarian cancer patients." Asia Pac J Clin Nutr. 13, Suppl:S116, 2004.

80. Saffair Y, Sadrzadeh SM. "Green tea metabolite EGCG protects membranes against oxidative damage in vitro." Life Sci. 74, 12:1513-8, 2004. www.sciencedirect.com/science/journal/00243205

81. Wei DZ et al. "Inhibition of liver cancer cell proliferation and migration by a combination of (-)-epigallocatechin-3-gallate and ascorbic acid." J Chemother. 15, 6:591-5, 2003.

82. Borska S et al. "Induction of apoptosis by EGCG in selected tumour cell lines in vitro." Folia Histochem Cytobiol. 41, 4:229-32, 2003.

83. Yokoyama M et al. "The tea polyphenol, (-)-epigallocatechin gallate effects on growth, apoptosis and telomerase activity in cervical cell lines." Gynecol Oncol. 92, 1:197-204, 2004. www.elsevier.com/locate/issn/0090-8258

84. Anh WS et al. "A major constituent of green tea, EGCG, inhibits the growth of a human cervical cancer cell line, CaSki cells, through apoptosis, G(1) arrest and regulation of gene expression." DNA Cell Biol. 22, 3:217-24, 2003.

85. Mittal A et al. "EGCG down-regulates telomerase in human breast carcinoma MCF-7 cells, leading to suppression of cell viability and induction of apoptosis." Int J Oncol. 24, 3:703-10, 2004. www.erlbaum.com/Journals/journals/NC/nc.htm

86. Zhou JR et al. "Soy phytochemicals and tea bioactive components synergistically inhibit androgen-sensitive human prostate tumors in mice." J Nutr. 133, 2:516-21, 2003. www.nutrition.org

87. Zhou JR et al. "Combined inhibition of estrogen-dependent human breast carcinoma by soy and tea bioactive components in mice." Int J Cancer. 108, 1:8-14, 2004. www3.interscience.wiley.com

88. Wu AH et al. "Green tea and risk of breast cancer in Asian Americans." Int J Cancer. 106, 4:574-9, 2003. www3.interscience.wiley.com

89. Yan L, Li D, Yee JA. "Dietary supplementation with isolated soy protein reduces metastasis of mammary carcinoma cells in mice." Clin Exp Metastasis. 19, 6:535-40, 2002. www.kluweronline.com/issn/0262-0898/contents

90. Jakes RW et al. "Mammographic parenchymal patterns and self-reported soy intake in Singapore Chinese women." Cancer Epidemiol Biomarkers Prev. 11, 7:608-13, 2002. http://cebp.aacrjournals.org/

91. Sarkar FH, Li Y. "Soy isoflavones and cancer prevention." Cancer Invest. 21, 5:744-57, 2003.

92. Peeters PH et al. "Phytoestrogens and breast cancer risk: Review of the epidemiological evidence." Breast Cancer Res Treat. 77, 2:171-83, 2003. http://cancerres.aacrjournals.org

93. Wood CE et al. "Breast and uterine effects of soy isoflavones and conjugated equine estrogens in postmenopausal female monkeys." J Clin Endocrinol Metab. 89, 7:3462-8, 2004. http://jcem.endojournals.org

94. Hussain M et al. "Soy isoflavones in the treatment of prostate cancer." Nutr Cancer. 47, 2:111-7, 2003. www.erlbaum.com/Journals/journals/NC/nc.htm

95. Kumar NB et al. "The specific role of isoflavones in reducing prostate cancer risk." Prostate. 59, 2:141-7, 2004.

96. Jarred RA et al. "Induction of apoptosis in low- to moderate-grade human prostate carcinoma by red clover-derived dietary isoflavones." Cancer Epidemiol Biomarkers Prev. 11, 12:1689-96, 2002. http://cebp.aacrjournals.org/

97. Atkinson C et al. "Red clover-derived isoflavones and mammographic breast density: a double blind, randomized, placebo-controlled trial." Breast Cancer Res. 6, 3:R170-9, 2004. http://breast-cancer-research.com/

98. Powles T. "Isoflavones and women's health." Breast Cancer Res. 6, 3:140-2, 2004. http://breast-cancer-research.com/

99. McCann SE et al. "Dietary lignan intakes and risk of pre- and postmenopausal breast cancer." Int J Cancer. 111, 3:440-3, 2004. www3.interscience.wiley.com

100. Linseisen J et al. "Dietary phytoestrogen intake and premenopausal breast cancer risk in a German case-control study." Int J Cancer. 110, 2:284-90, 2004. www3.interscience.wiley.com

101. McCann SE et al. "The risk of breast cancer associated with dietary lignans differs by CYP17 genotype in women." J Nutr. 132, 10:3036-41, 2002. www.nutrition.org

102. Chen J et al. "Exposure to flaxseed or its purified lignan during suckling inhibits chemically induced rat mammary tumorigenesis." Exp Biol Med (Maywood). 228, 8:951-8, 2003. www.ebmonline.org

103. Chen J, Stavro PM, Thompson LU. "Dietary flaxseed inhibits human breast cancer growth and metastasis and downregulates expression of insulin-like growth factor and epidermal growth factor receptor." Nutr Cancer. 43, 2:187-92, 2002. www.erlbaum.com/Journals/journals/NC/nc.htm

104. Thompson Lu et al. "Biological effects of dietary flaxseed in patients with breast cancer." Breast Cancer Res Treat. 64:50, 2000. http://cancerres.aacrjournals.org

105. Goss et al. "Effects of dietary flaxseed in women with cyclical mastalgia." Breast Cancer Res Treat. 64:49, 2000. http://cancerres.aacrjournals.org

106. Lin X et al. "Effect of flaxseed supplementation on prostatic carcinoma in transgenic mice." Urology. 60, 5:919-24, 2002. http://www.goldjournal.net/

107. Duncan AM. "The role of nutrition in the prevention of breast cancer." AACN Clin Issues. 15, 1:119-35, 2004.

108. Jho DH et al. "Eicosapentaenoic acid supplementation reduces tumor volume and attenuates cachexia in a rat model of progressive non-metastasizing malignancy." JPEN J Parenter Enteral Nutr. 26, 5:291-7, 2002.

109. Nkondjock A, Ghadirian P. "Intake of specific carotenoids and essential fatty acids and breast cancer risk in Montreal, Canada." Am J Clin Nutr. 79, 5:857-64, 2004. www.ajcn.org

110. Wasser SP. "Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides" Appl Microbiol Biotechnol. 60, 3:258-74, 2002.

111. Borchers AT, Keen CL, Gershwin ME. "Mushrooms, tumors and immunity: an update." Exp Biol Med (Maywood). 229, 5:393-406, 2004. www.ebmonline.org

112. Jiang J et al. "Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3." Int J Oncol. 24, 5:1093-9, 2004. www.erlbaum.com/Journals/journals/NC/nc.htm

113. Wachtel-Galor S, Tomlinson B, Benzie IF. "Ganoderma lucidum ("Lingzhi"), a Chinese medicinal mushroom: biomarker responses in a controlled human supplementation study." Br J Nutr. 91, 2:263-9, 2004. www.cabi-publishing.org/journals/bjn

114. Ng ML, Yap AT. "Inhibition of human colon carcinoma development by lentinan from shiitake mushrooms (Lentinus edodes)." J Altern Comp Med. 8, 5:581-9, 2002. www.liebertpub.com

115. deVere White RW et al. "Effects of a mushroom mycelium extract on the treatment of prostate cancer." Urology. 60, 4:640-4, 2002. http://www.goldjournal.net/

116. Ohno N et al. "Antitumor beta glucan from the cultured fruit body of Agaricus blazei." Biol Pharm Bull. 24, 7:820-8, 2001.

117. Oshiman K et al. "Orally administered beta-1,6-D-polyglucose extracted from Agaricus blazei results in tumor regression in tumor-bearing mice." Planta Med. 68, 7:610-4, 2002.

118. Barbisan LF et al. "Effects of crude extracts of Agaricus blazei on DNA damage and on rat liver carcinogenesis induced by diethylnitrosamine." Genet Mol Res. 2, 3:295-308, 2003.

119. Ahn WS et al. "Natural killer cell activity and quality of life were improved by consumption of a mushroom extract, Agaricus blazei Murill Kyowa, in gynecological cancer patients undergoing chemotherapy." Int J Gynecol Cancer. 14, 4:589-94, 2004.

120. Mayell M. "Maitake extracts and their therapeutic potential." Altern Med Rev. 6, 1:48-60, 2001. www.thorne.com/altmedrev

121. Kodama N et al. "Effects of D-Fraction, a polysaccharide from Grifola frondosa on tumor growth involve activation of NK cells." Biol Pharm Bull. 25, 12:1647-50, 2002.

122. Kodama N, Murata Y, Nanba H. "Administration of a polysaccharide from Grifola frondosa stimulates immune function of normal mice." J Med Food. 7, 2:141-5, 2004. www.liebertpub.com

123. Kodama N, Komuta K, Nanba H. "Effect of Maitake (Grifola frondosa) D-Fraction on the activation of NK cells in cancer patients." J Med Food. 6, 4:371-7, 2003. www.liebertpub.com

124. Kodama N, Komuta K, Nanba H. "Can maitake MD-fraction aid cancer patients?" Altern Med Rev. 7, 3:236-9, 2002. www.thorne.com/altmedrev

125. Lin H et al. "Maitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro." Int Immunopharmacol. 4:91-9, 2004. www.elsevier.com/locate/intimp

126. Uno K et al. "Active Hexose Correlated Compound (AHCC) improves immunological parameters and performance status of patients with solid tumors." Biotherapy. 14, 3:303-9, 2000. www.kluweronline.com/issn/0921-299X/current.

127. Yagita A et al. "H-2 haplotype-dependent serum IL-12 production in tumor-bearing mice treated with various mycelial extracts." In Vivo. 16, 1:49-54, 2002.

128. Matsui Y et al. "Improved prognosis of postoperative hepatocellular carcinoma patients when treated with functional foods: a prospective cohort study." J Hepatol. 37, 1:78-86, 2002. www.jhep-elsevier.com

129. Jiang D. "Clinical observation of stage M1 malignant tumors treated with the combination of chemotherapy and AHCC." 12th International Symposium of AHCC Research Association, July 24-25, 2004.

130. Hong SJ et al. "The effect of Genistein Combined Polysaccharide (GCP) and Active Hexose Correlated Compound (AHCC) mixture, GAC (Angiogen), on the reduction of side effects and the improvement of quality of life in prostate cancer patients with androgen suppression." 12th International Symposium of AHCC Research Association, July 24-25, 2004.

131. Ghafar MA et al. "Regression of prostate cancer following administration of Genistein Combined Polysaccharide (GCP), a nutritional supplement: a case report." J Altern Comp Med. 8, 4:493-7, 2002. www.liebertpub.com

132. Bemis DL et al. "A concentrated aglycone isoflavone preparation (GCP) that demonstrates potent anti-prostate cancer activity in vitro and in vivo." Clin Cancer Res. 10, 15:5282-92, 2004.

133. Hong F et al. "Mechanism by which orally administered beta-1,3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models." J Immunol. 173:797-806, 2004.

134. Pugh N et al. "Isolation of three high molecular weight polysaccharide preparations with potent immunostimulatory activity from Spirulina platensis, aphanizomenon flos-aquae and Chlorella pyrenoidosa." Planta Med. 67, 8:737-42, 2001.

135. Justo GZ, Silva MR, Queiroz ML. "Effects of the green algae Chlorella vulgaris on the response of the host hematopoietic system to intraperitoneal ehrlich ascites tumor transplantation in mice." Immunopharmacol Immunotoxicol. 23, 1:119-32, 2001. www.dekker.com/servlet/product/productid/IPH

136. Thomson M, Ali M. "Garlic [Allium sativum]:a review of its potential use as an anti-cancer agent." Curr Cancer Drug Targets. 3, 1:67-81, 2003.

137. Das S. "Garlic--A natural source of cancer preventive compounds." Asian Pac J Cancer Prev. 3, 4:305-11, 2002.

138. Oommen S et al. "Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells." Eur J Pharmacol. 485, 1-3:97-103, 2004.

139. Berges R et al. "Comparison of the chemopreventive efficacies of garlic powders with different alliin contents against aflatoxin B1 carcinogenicity in rats." Carcinogenesis. Epub ahead of print. June 3, 2004. http://carcin.oupjournals.org

140. Tilli CM et al. "The garlic-derived organosulfur component ajoene decreases basal cell carcinoma tumor size by inducing apoptosis." Arch Dermatol Res. 295, 3:117-23, 2003.

141. Sundaresan S, Subramanian P. "S-allylcysteine inhibits circulatory lipid peroxidation and promotes antioxidants in N-nitrosodiethylamine-induced carcinogenesis." Pol J Pharmacol. 55, 1:37-42, 2003.

142. Lu HF et al. "Diallyl disulfide (DADS) induced apoptosis undergo caspase-3 activity in human bladder cancer T24 cells." Food Chem Tox. 42, 10:1543-52, 2004. www.elsevier.nl/locate/foodchemtox

143. Aggarwal BB, Kumar A, Bharti AC. "Anticancer potential of curcumin: preclinical and clinical studies." Anticancer Res. 23, 1A:363-98, 2003. www.geocities.com/Athens/Rhodes/8729/iiar/iiar.htm

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